“After using this cream consistently, the fine lines on my face look noticeably softer, and even my deeper lines appear smoother and less pronounced.”
Marina P.Jun 2026
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Firming
Smoothing
Hydrating
Brightening
Nourishing
Renewing
- Made in South Korea
- ISO 22716 · Cosmetic GMP
- ISO 9001 · Quality management
- ISO 14001 · Environmental management
- Fine lines & wrinkles
- Loss of firmness
- Crepey, dull-looking skin
- Dryness & dehydration
Your personalized match
Face & Neck · Peptide Firming
Crème Régénérante™
Firmer, smoother, more youthful-looking
Powered by VYPR-2™, an advanced lab-made peptide. Paired with other powerful actives, this cream soothes, hydrates, and firms the look of skin.
Only $1.33 a day to look younger
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Based on your answers
Firms
Firmer along jaw & neck
Built on the VYPR-2™ peptide
Smooths
Softer expression lines
Adenosine + peptide actives
Hydrates
Deep hydration that lasts all day
Sodium hyaluronate + shea butter
Gentle
Safe for sensitive skin
Non-greasy, comforting daily formula
Before & after
Before
After
Softer lines, hydrated skin
“The lines around my mouth look softer and my skin stays hydrated all day. I only wish I'd started sooner.”
Ann T.8 weeks
Before
After
More even, less dull
“My tone looks more even and my skin finally looks awake again. The dullness I'd gotten used to is just gone.”
Sofía M.12 weeks
Before
After
Calmer, hydrated skin
“The dry, tight patches on my cheeks calmed right down and my skin feels hydrated and comfortable all day.”
Layla H.10 weeks
Before
After
Dull skin, now glowing
“My skin always looked dull and tired. Now the tone looks even and I've got a healthy glow I hadn't seen in years.”
Karin B.12 weeks
Firming, without the needle.
$435+
Botox per session
fades in a few months
$715+
Dermal filler per syringe
clinic visit required
Not like other firming creams
Most creams only chase the lines you already have. This works in both directions, at once.
Your match
Other firming creams
Crème Régénérante™
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✕Corrects existing lines only✓Delays new lines and softens existing ones — both directions, powered by VYPR-2™
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✕A generic base that fades by midday✓A moisturizer base that holds hydration all day — visibly brighter, more radiant skin from the first use
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✕No tool, no gift box✓Weighted sculpting spatula and gift box included
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✕One-size-fits-all ingredients✓Every ingredient researched, each with a real purpose — Earth · Lab · Skin
Formulated with actives
clinically shown to
52%
Reduce wrinkle depth
VYPR-2™ Dipeptide · 28 days
DSM / Pentapharm · n=15
DSM / Pentapharm · n=15
96%
Improve skin hydration
Sodium Hyaluronate
Pavicic et al. 2011 · n=76 · 60 days
Pavicic et al. 2011 · n=76 · 60 days
3weeks
Smooth the look of fine lines
Adenosine · Abella 2006
n=126 · MFDS-recognised active
n=126 · MFDS-recognised active
Results, on a realistic timeline
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Day 1Instant hydration
Dull, tired-looking skin with fine lines. It instantly feels nourished and hydrated.
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Week 2Lines start to soften
The look of fine lines starts to soften where they show most.
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Week 4–6Smoother & more even
Skin looks smoother, more even and radiant.
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Week 8–12Firmer & healthier
Firmer-looking, smoother, healthier skin with continued daily use.
VYPR-2™ · The architect
One peptide
does the work.
VYPR-2™ is a biomimetic dipeptide modeled on waglerin-1 — a peptide found in the venom of the Temple Viper, long noted for a firming effect. There is no venom in the formula. VYPR-2™ is built entirely in the lab to mimic that effect on skin.
Mimic
Inspired by the Temple Viper
Modeled on waglerin-1, a peptide known for visibly firming skin.
Bind
Works at the surface
Sinks in where expression lines first take hold.
Delay
Softens lines before they set
Helps delay the look of new lines, while softening today's.
No venom. No needles. A peptide engineered for daily, topical use.
Every ingredient
has a purpose.
Derived from three sources — Earth, Lab, and Skin.
Earth
Shea ButterA rich plant butter that cushions the surface and relieves the tight, rough feel of dry, depleted skin.
Sunflower Seed OilA featherlight oil that absorbs fast without grease, carrying the actives in and leaving skin soft and smooth.
Lemon Peel OilThe fresh citrus note behind the cream's clean, uplifting scent — a small sensory cue that makes the daily solution easy to keep.
Cedarwood OilA soft, woody warmth that rounds out the scent with a calm, grounding feel as you massage it in.
Lab
VYPR-2™The hero firming peptide — lab-made, modeled on a peptide first found in snake venom (there's none in the formula). It targets the look of expression lines and helps skin look firmer over time.
NiacinamideVitamin B3, one of skincare's most-studied actives — helps even the look of tone for a clearer, more uniform complexion.
AdenosineAn anti-wrinkle active recognized by Korea's MFDS — supports the look of resilience and softens the appearance of fine lines.
TromethamineThe quiet workhorse that balances the formula's pH, keeping every active stable and effective from the first use to the last.
Skin
Sodium HyaluronateA skin-identical moisture-binder that holds water in the upper layers, so skin looks plumper, dewier, and stays hydrated all day.
PanthenolPro-vitamin B5 that comforts and reinforces the moisture barrier, leaving skin feeling soft, soothed, and less prone to tightness.
TocopherolVitamin E — an antioxidant that conditions skin and helps defend against the everyday environmental stress it faces.
Caprylic TriglycerideA silky, ultra-light emollient that gives the cream its smooth glide and a clean, weightless finish that never feels greasy.
Full ingredient list
Water, Glycerin, Caprylic/Capric Triglyceride, Butylene Glycol, Butyrospermum Parkii (Shea) Butter, 1,2-Hexanediol, Niacinamide, Cetearyl Alcohol, Glyceryl Stearate, Behenyl Alcohol, Panthenol, Vinyl Dimethicone, Polyglyceryl-2 Stearate, Stearyl Alcohol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Fragrance, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Ethylhexylglycerin, Adenosine, Disodium EDTA, Citrus Limon (Lemon) Peel Oil, Sodium Hyaluronate, Juniperus Virginiana Oil, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Limonene.
What early users notice
“I've been testing this face cream for a few weeks and I honestly love it. My skin feels deeply hydrated, nourished, and glowing.”
LikaMay 2026
“I can see a real difference in my skin. It feels much softer, more hydrated, and looks healthier overall — without any irritation.”
Arthur G.May 2026
“Good cream. My skin feels softer and stays hydrated, and it sinks in without any grease. It took a few weeks before I really noticed a difference, and I'd love a slightly bigger jar — but I'm happy with it.”
Elena K.Jun 2026
“I'm 61 and my neck has always been my worry. After two months it genuinely looks firmer and smoother, and the little tool makes the routine feel like a treatment.”
Susan M.Jun 2026
“My cheeks look plumper and the lines around my mouth have softened. It sinks in fast and layers beautifully under makeup.”
Patricia L.Jun 2026
“The most hydrating cream I've tried. My skin feels comfortable all day and looks noticeably smoother. Worth every penny.”
Grace H.May 2026
“Honestly didn't expect much, but my skin looks brighter and feels firm and smooth. It absorbs instantly and never feels greasy — I'm already on my second jar.”
Dana R.May 2026
“I've repurchased three times now. Firmer-looking jawline, no irritation on my sensitive skin, and a lovely light scent. This has become my forever cream.”
Deborah W.Jun 2026
Individual results vary. Efficacy figures reflect published studies of individual active ingredients, not the finished product.
Try it with a 30-day money-back guarantee
Give it a few weeks. If it isn't right for you, we'll make it right. Unopened jars, full refund within 30 days; opened and not for you, just email us.
Frequently asked questions
No. There is no venom in the formula. VYPR-2™ is a peptide built in the lab, modeled on a protein found in the venom of the Temple Viper — designed to mimic its firming effect, with none of the venom.
From the first application, skin looks brighter, feels nourished and stays hydrated. The look of firmer skin and softened fine lines builds more gradually, over a few weeks of consistent daily use.
Used morning and night as directed, a pea-size amount means one jar lasts most people about 30 to 45 days.
Yes — it's a face and neck firming cream. Use the same pea-size amount and sweep it down the jawline and neck, where firmness and crepey-looking skin tend to show first. The weighted spatula is made for those upward strokes.
A pea-size amount covers the full face and neck. Morning: after serums, before sunscreen and makeup. Night: as your last step — it layers over treatments like retinol and doubles as a moisturizer.
No venom, and never tested on animals. The cream is made in South Korea under ISO 22716 (cosmetic GMP), ISO 9001 and ISO 14001 standards.
30 days on unopened jars for a full refund. Opened and not right for you? Email info@synerainnovations.com and the team will help.
Start your firming solution.
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- ✓ Crème Régénérante™ — 50 g / 1.76 oz full size
- ✓ Weighted sculpting spatula included
- ✓ 30-day money-back guarantee
- ✓ Free shipping over $100
- ✓ Secure, encrypted checkout
- ✓ Made in Korea · ISO-certified lab · cruelty-free
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